Histidine Targeting Heterobimetallic Ruthenium(II)–Gold(I) Complexes

Selective nitrite reduction at heterobimetallic CoMg complexes.

Heme-containing nitrite reductases bind and activate nitrite by a mechanism that is proposed to involve interactions with Brønsted acidic residues in the secondary coordination sphere. To model this functionality using synthetic platforms that incorporate a Lewis acidic site, heterobimetallic CoMg complexes supported by diimine-dioxime ligands are described. The neutral (μ-NO2)CoMg species 3 is...

Characterization and reactivity of peralkylated LnIIAlIII heterobimetallic complexes.

The heterobimetallic peralkylated complexes [Ln(AlR4)2]n (Ln = Sm, Yb; R = Me, Et) were synthesized by a silylamide elimination route from Ln[N(SiMe3)2]2(THF)2 and an excess of AlR3. The solid-state structure of [Sm(AlEt4)2]n is isomorphous to that of the ytterbium derivative. Polymeric [Yb(AlMe4)2]n was examined by 1H and 13C MAS NMR spectroscopy revealing the presence of distinct bridging met...

Heterobimetallic complexes with highly flexible 1,1'-bis(phospholanoalkyl)ferrocene ligands.

The two highly flexible ligands 1,1'-bis(4-phospholanobutyl)ferrocene (5a) and 1,1'-bis(5-phospholanopentyl)ferrocene (5b) reacted with [PtCl2(cod)] (cod = 1,5-cyclooctadiene), [AuCl(tht)] (tht = tetrahydrothiophene) and [{RhCl(CO)2}2] to give the respective chelate complexes cis-[PtCl2(5a,b-κ(2)P,P')] (7a,b), [AuCl(5a,b-κ(2)P,P')] (8a,b) and trans-[RhCl(CO)(5b-κ(2)P,P')] (9b). Treatment of 5a,...

Cupric ion complexes of histidine-containing peptides.

The binding of cupric or zinc ion by sperm whale metmyoglobin appears to involve imidazole groups of histidyl residues (4, 5) that occur well removed from the NH2 terminus (6). The binding of each cupric ion by metmyoglobin is accompanied on the average by the displacement of one or more protons beyond that that may be borne by the imidazole group, presumably from peptide amide nitrogen atoms (...

Mercury(II) Complexes of Imidazole and Histidine